Key result
Young patients with relapsing-remitting multiple sclerosis had significantly increased daily vascular wall stiffness (p<0.001) and reduced daytime blood pressure variability compared to healthy controls.
Why the study?
The study was conducted to evaluate the state of the cardiovascular system and peripheral microcirculation in young patients with relapsing-remitting multiple sclerosis.
Do young patients with relapsing-remitting multiple sclerosis exhibit early markers of increased cardiovascular risk compared to healthy controls?
Case-Control (n=60)
Do young patients with relapsing-remitting multiple sclerosis exhibit early markers of increased cardiovascular risk compared to healthy controls?
Young patients with relapsing-remitting multiple sclerosis exhibit early markers of increased cardiovascular risk, including altered blood pressure variability, increased vascular stiffness, and elevated ICAM-1 levels.
Young RRMS patients show reduced daytime BP variability and elevated VCAM-1; leaves open whether targeted CV screening improves outcomes.
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Traktirskaya et al. (2019) conducted a case-control in Relapsing-remitting multiple sclerosis (n=60). Relapsing-remitting multiple sclerosis vs. Healthy individuals was evaluated on Daily vascular wall stiffness (p=<0.001). Young patients with relapsing-remitting multiple sclerosis had significantly increased daily vascular wall stiffness (p<0.001) and reduced daytime blood pressure variability compared to healthy controls.
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