Why the study?
Do patients with systemic sclerosis exhibit early preclinical alterations in cardiac autonomic control and cardiac function compared to healthy controls?
Do patients with systemic sclerosis exhibit early preclinical alterations in cardiac autonomic control and cardiac function compared to healthy controls?
Noninvasive evaluation using 24-hour Holter monitoring and echocardiography can detect early preclinical cardiac autonomic dysfunction and diastolic impairment in patients with systemic sclerosis.
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Suggests subclinical autonomic dysfunction in systemic sclerosis; hypothesis-generating and should not yet change monitoring practices.
Othman et al. (2010) studied this question.
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