Key result
Systemic scleroderma without evident heart disease was associated with increased premature supraventricular and ventricular contractions and decreased heart rate variability compared to controls.
Why the study?
Do noninvasive electrocardiographic methods detect early subclinical heart involvement in patients with systemic scleroderma?
Case-Control (n=27)
Do noninvasive electrocardiographic methods detect early subclinical heart involvement in patients with systemic scleroderma?
Noninvasive electrocardiographic evaluation, including Holter monitoring and HRV analysis, is useful for detecting early, subclinical cardiac involvement in patients with systemic scleroderma.
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Suggests subclinical autonomic dysfunction in asymptomatic SSc; leaves open whether HRV/HRT predict outcomes.
Biełous‐Wilk et al. (2009) conducted a case-control in Systemic scleroderma (n=27). Systemic scleroderma vs. Control group was evaluated on Electrocardiographic changes, parameters of heart rate variability (HRV), and heart rate turbulence (HRT). Systemic scleroderma without evident heart disease was associated with increased premature supraventricular and ventricular contractions and decreased heart rate variability compared to controls.
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