A core-shell-type nanosystem promotes diabetic wound healing through Photothermal-responsive release of transforming growth factor β

This is the authors' abstract. We don't add key points for this paper.

Diabetic wounds are the most common complication of diabetes, contributing to severe health costs and economic losses [ 1 ]. Over 1 million patients with diabetes present with diabetic wounds [ 2 , 3 ]. Therefore, developing new wound dressings is essential for treating diabetic wounds [ 4 ]. However, treating diabetic wounds remains challenging because a high-glucose microenvironment can further induce bacterial breeding, resulting in infection-related complications [ 2 , 5 ]. Microangiopathy and revascularization defects can also negatively influence healing [ 6 , 7 ]. The infections and defects of vessels might further trigger a chain of adverse reactions, such as inhibition of cell proliferation and migration [ 8 , 9 ].