Key result
Enhanced external counterpulsation significantly improved exercise tolerance in patients with CAD and heart failure, increasing 6-minute walk distance by 44.6% at 3 months and 34.3% at 6 months (p<0.05).
Why the study?
The mid-term effects of enhanced external counterpulsation on vascular structural and functional parameters, exercise tolerance, and quality of life in coronary artery disease were evaluated.
Does enhanced external counterpulsation improve exercise tolerance, quality of life, and vascular function in patients with stable coronary artery disease and chronic heart failure?
Population
70 patients with stable CAD and NYHA class II-III heart failure
Comparison
Course of EECP (35 hours procedures)
Design
Single-arm prospective study
Follow-up
6 months
Authors
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Should not yet change practice in CAD with HF; hypothesis-generating pending randomized confirmation.
Does enhanced external counterpulsation improve exercise tolerance, quality of life, and vascular function in patients with stable coronary artery disease and chronic heart failure?
Effect estimate: 44.6% increase at 3 months
p-value: p=<0.05
A course of enhanced external counterpulsation provides sustained improvements in exercise tolerance and quality of life up to 6 months in patients with stable CAD and heart failure, although improvements in vascular endothelial function appear transient.
Karaganov et al. (2021) studied Coronary artery disease with chronic heart failure (n=65). Enhanced external counterpulsation (EECP) was evaluated on Exercise tolerance (6-minute walk test distance) (44.6% increase at 3 months, p=<0.05). Enhanced external counterpulsation significantly improved exercise tolerance in patients with CAD and heart failure, increasing 6-minute walk distance by 44.6% at 3 months and 34.3% at 6 months (p<0.05).
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