Key result
A 55-year-old male with undiagnosed advanced lung cancer presented with stroke symptoms due to direct tumor invasion into the left atrium and mixed embolic showering phenomenon.
Why the study?
Cardiac invasion and vascular tumor seeding from advanced lung cancer present clinical challenges, with fewer than ten cases of spontaneous tumor embolization from pulmonary vein invasion previously reported.
Case Report (n=1)
Highlights a rare presentation of advanced lung cancer with direct cardiac invasion and spontaneous tumor embolization causing stroke.
Alerts clinicians to evaluate for cardiac invasion in lung cancer patients with embolic stroke; leaves open optimal management strategies for this rare presentation.
Advanced lung cancer can have numerous extra-pulmonary complications. Due to the proximity to the heart, cardiac invasion and the subsequent seeding of the tumor into the vascular system present numerous challenges in physician team care coordination. Here we have a 55-year-old male who presented with stroke symptoms in the setting of undiagnosed advanced lung cancer complicated by direct tumor invasion into the left atria and mixed embolic showering phenomenon and thrombotic hypercoagulability. Review of both the embolic showering phenomenon and hypercoagulability will be discussed as both can result in embolic occlusion or metastatic seeding at distant sites. Fewer than ten cases of spontaneous tumor embolization resulting from lung cancer invasion of the pulmonary vein have been reported. Poor prognosis of advanced lung cancer requires delicate, yet pragmatic conversations between care teams and the patient.
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Chin et al. (2020) conducted a case report in Advanced lung cancer with cardiac invasion (n=1). Advanced lung cancer with cardiac invasion was evaluated. A 55-year-old male with undiagnosed advanced lung cancer presented with stroke symptoms due to direct tumor invasion into the left atrium and mixed embolic showering phenomenon.
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