Key result
Administration of a bait vaccine completely protected boar-pig hybrids from clinical signs, pathological manifestations, and viremia following experimental infection with a recent Japanese CSFV isolate.
Why the study?
To analyze the pathogenicity of a recent Japanese classical swine fever virus in wild boars using boar-pig hybrids and evaluate the effectiveness of a bait vaccine.
Does a bait vaccine prevent clinical signs of classical swine fever virus infection in boar-pig hybrids?
Does a bait vaccine prevent clinical signs of classical swine fever virus infection in boar-pig hybrids?
Absolute Event Rate: 0% vs 100%
A bait vaccine is effective in preventing clinical signs of a recent Japanese classical swine fever virus isolate in boar-pig hybrids.
Bait vaccine prevented signs in infected hybrids; leaves open field efficacy for CSFV control in wild boars.
We analyzed the pathogenicity of a recent Japanese classical swine fever virus (CSFV) to wild boars via an experimental infection using boar-pig hybrids as an alternative to wild boars. We also investigated the effectiveness of a bait vaccine against the CSFV. Naïve boar-pig hybrids and pigs showed clinical signs such as fever, leucopenia, anorexia and conjunctivitis following the experimental infection. In contrast, the boar-pig hybrids administered the bait vaccine did not show any clinical signs. Our data indicated that boar-pig hybrids and domestic pigs have similar susceptibility to the recent Japanese CSFV. Additionally, the bait vaccine is effective against the CSFV.
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Fukai et al. (2020) studied Classical swine fever (n=9). Bait vaccine (RIEMSER Schweinepestoralvakzine) vs. Naïve (unvaccinated) animals was evaluated on Development of clinical signs and viremia after CSFV infection. Administration of a bait vaccine completely protected boar-pig hybrids from clinical signs, pathological manifestations, and viremia following experimental infection with a recent Japanese CSFV isolate.
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