Key result
Chest pain duration of eight hours or longer during a first myocardial infarction was associated with higher cardiac enzymes, greater ST segment elevation, and larger cardiac volumes.
Why the study?
Does chest pain duration of eight hours or longer correlate with larger infarct size in patients with first myocardial infarction?
Population
70 patients with first myocardial infarcts
Comparison
Chest pain duration eight hours or longer (n=35) vs Chest pain duration less than eight hours (n=35)
Design
Cohort
Authors
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May flag larger first-MI size; leaves open whether duration improves risk stratification or outcomes.
Observational (n=70)
Does chest pain duration of eight hours or longer correlate with larger infarct size in patients with first myocardial infarction?
Prolonged chest pain duration (≥8 hours) during a first myocardial infarction may serve as a clinical indicator of larger infarct size.
J. R. Ledwich (1980) conducted an observational in First myocardial infarction (n=70). Chest pain duration ≥8 hours vs. Chest pain duration <8 hours was evaluated on Indicators of infarct size (creatine phosphokinase, SGOT, ST segments, transmural infarcts, cardiac volumes, temperature, WBC counts). Chest pain duration of eight hours or longer during a first myocardial infarction was associated with higher cardiac enzymes, greater ST segment elevation, and larger cardiac volumes.