Key result
This review outlines the mechanisms of hypertension in renal failure and presents a treatment paradigm for combination antihypertensive drug therapy to improve kidney function outcomes.
This review outlines the mechanisms, treatment goals, and a paradigm for combination antihypertensive therapy in patients with renal failure.
May guide combination antihypertensive strategies in renal failure; leaves open prospective validation of the proposed paradigm before practice change.
Hypertension is a common component of the morbidity associated with renal failure. The mechanisms that contribute to high blood pressure are reviewed in this section. Also covered are therapies to reduce hypertension, the treatment goals of those therapies, and the outcomes of antihypertensive therapy on kidney function in patients with renal failure. Various antihypertensive agents are specifically addressed, and a treatment paradigm is presented for combination antihypertensive drug therapy, which is usually necessary in the antihypertensive therapy of patients with renal failure.
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Townsend et al. (1998) conducted a review in Hypertension in renal failure. Antihypertensive therapy was evaluated. This review outlines the mechanisms of hypertension in renal failure and presents a treatment paradigm for combination antihypertensive drug therapy to improve kidney function outcomes.
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