Answers are grounded in this paper and cite their sources.
Stereospecific nickel-catalyzed cross-coupling reactions of benzylic 2-methoxyethyl ethers are reported for the preparation of enantioenriched 1,1-diarylethanes. The 2-methoxyethyl ether serves as a traceless directing group that accelerates cross-coupling. Chelation of magnesium ions is proposed to activate the benzylic C-O bond for oxidative addition.
No takes yet. Share an insight, caveat, or question.
Greene et al. (2012) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: