Key result
Primary hepatic angiosarcoma can lack FDG-avid lesions on PET imaging, demonstrating FDG uptake similar to that of normal liver parenchyma.
Primary hepatic angiosarcoma may not show increased FDG uptake on PET imaging, appearing similar to normal liver parenchyma.
Negative FDG PET does not exclude hepatic angiosarcoma; leaves open optimal imaging strategies for this rare tumor.
Primary hepatic angiosarcoma is a rare but aggressive malignancy. A 60-year-old woman presented with multiple liver lesions with progressive enhancement detected with multiphasic CT. FDG PET did not show any FDG-avid lesions, and the uptake of hepatic lesions was similar to that of the normal liver parenchyma. Subsequently, pathological examination revealed hepatic angiosarcoma.
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Wang et al. (2022) studied this question. Primary hepatic angiosarcoma can lack FDG-avid lesions on PET imaging, demonstrating FDG uptake similar to that of normal liver parenchyma.
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