What question did this study set out to answer?

Assess the acute hemodynamic effects of transvenous electrical pacing at rest and during physical exercise in individuals with complete heart block and cardiac failure.

January 1, 1969CirculationOpen Access

Immediate Hemodynamic Response of Patients with Atrioventricular Block and Cardiac Failure to Transvenous Pacing

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Why the study?

Does transvenous pacing improve immediate hemodynamics in patients with atrioventricular block and cardiac failure?

Population

Patients with atrioventricular block (complete heart block) and cardiac failure

Comparison

Transvenous electrical pacing to increase… vs Unpaced state

Follow-up

Immediate

Authors

FGFredarick L. GobelCedars-Sinai Medical Center JMJosé R. MedinaArizona State University CGC. A. GuenterVictoria General Hospital

Discussion

Member takes

Implication

May improve acute exercise hemodynamics in complete heart block; leaves open effects on contemporary clinical outcomes.

Key Points

Assess the acute hemodynamic effects of transvenous electrical pacing at rest and during physical exercise in individuals with complete heart block and cardiac failure.
Monitored intracardiac hemodynamics, filling pressures, and dye-dilution curves in patients with complete heart block and heart failure during unpaced rhythm and transvenous electrical pacing.
Evaluated changes in cardiac performance both under resting conditions and during physical exercise.
Electrical pacing immediately reduced pulmonary artery wedge, right atrial, and biventricular filling pressures, while resting cardiac output showed minimal change.
Pacing decreased stroke volume, stroke work, and mean ejection rate at rest, while prolonging ejection time per minute and normalizing dye-dilution curves.
During exercise, paced hearts achieved greater gains in cardiac output, stroke volume, and ejection rate compared to unpaced states, alongside normalization of elevated filling pressures.

Structured PICO

Does transvenous pacing improve immediate hemodynamics in patients with atrioventricular block and cardiac failure?

Population

Patients with atrioventricular block (complete heart block) and cardiac failure

Intervention

Transvenous electrical pacing to increase ventricular rate

Comparator

Unpaced state

Outcome

Immediate hemodynamic response (including pulmonary artery wedge, right atrial, and ventricular filling pressures, cardiac output, stroke volume, and mean rate of ejection)surrogate

Transvenous pacing provides immediate hemodynamic benefits in patients with complete heart block and heart failure, particularly by improving cardiac output and stroke volume during exercise.

Cite This Study

Gobel et al. (1969) studied this question.

synapsesocial.com/papers/6a9e6ff7ea032eb126da2d23 https://doi.org/10.1161/01.cir.39.1.64

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Immediate Hemodynamic Response of Patients with Atrioventricular Block and Cardiac Failure to Transvenous Pacing

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Immediate Hemodynamic Response of Patients with Atrioventricular Block and Cardiac Failure to Transvenous Pacing

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Also Consider