Key result
Electroconvulsive shock in rhesus monkeys produced patterns of internal carotid blood flow and arterial pressure changes similar to those observed in dogs and psychotic patients.
Answers are grounded in this paper and cite their sources.
The study demonstrates that cardiovascular responses (blood flow and arterial pressure) to electroconvulsive shock in rhesus monkeys are similar to those observed in dogs and humans.
IN PREVIOUS papers we have reported that when the dog is used as an experimental animal the common carotid blood flow and arterial pressure responses to electroconvulsive shock and experimental concussion are similar.* Under the conditions of these experiments we inferred that the observed changes in common carotid blood flow were indicative of cerebral blood flow variations.2To test this hypothesis, a series of experiments were performed with electroconvulsive shock on rhesus macaque monkeys.3Measurement of the internal carotid blood flow in these animals indicates the status of cerebral blood flow.4The pattern of flow and pressure changes following electroconvulsive shock in the monkeys was similar to that obtained in dogs.3Furthermore, the pattern of arterial pressure responses following electroconvulsive shock therapy in psychotic patients is similar in time and direction of change to the pattern observed in dogs and monkeys after such stimuli.5 The
No takes yet. Share an insight, caveat, or question.
George W. Brown (1954) studied Experimental cerebral concussion. Electroconvulsive shock was evaluated on Internal carotid blood flow and arterial pressure changes. Electroconvulsive shock in rhesus monkeys produced patterns of internal carotid blood flow and arterial pressure changes similar to those observed in dogs and psychotic patients.
Synapse has enriched 10 related papers. Consider them for comparative context: