Key result
The seroprevalence of classical swine fever virus in apparently healthy unvaccinated pigs in Mizoram was 34.68%, while molecular detection in symptomatic vaccinated pigs was 11.60%.
Why the study?
Classical swine fever is a fatal endemic disease in pig populations of North eastern India and India in general.
Cross-Sectional (n=956)
Yes
The study confirms the endemicity of classical swine fever virus in the pig population of Mizoram, India, highlighting the need for improved vaccination and surveillance.
Classical swine fever (CSF) is a fatal endemic disease of pig population of North eastern India in particular and India in general. Present study revealed molecular detection of CSFV and seroprevalence of the disease in pig population of Mizoram, India during 2016–2018. Serum samples from apparently healthy, unvaccinated pigs were collected in collaboration with the State Animal Husbandry and Veterinary Department, Mizoram and a total of 594 serum samples from 7 districts were subjected to detection of CSFV specific antibodies by indirect ELISA. A total of 206 (34.68%) serum samples were positive for CSFV antibodies by ELISA. District wise, Saiha district showed highest seroprevalence of the disease followed by Kolasib and Serchhip. Apart from this, during the same time period, CSFV suspected samples received in the Department of Veterinary Microbiology consisting of 269 serum samples, 10 whole blood and 83 tissue samples obtained from 8 districts of Mizoram were subjected to detection of NS5b and E2 mRNA transcripts by nRT-PCR of which a total of 42 (11.60%) samples including serum (5.58%), tissues (27.71%) and whole blood (40%) were positive for the NS5b and E2 mRNA transcripts, specific for CSFV. District wise analysis revealed that Aizawl has the highest percentage of positive samples of CSFV followed by Saiha and Lawngtlai district.
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Kawlni et al. (2021) conducted a cross-sectional in Classical swine fever (CSF) (n=956). Classical swine fever virus (CSFV) exposure was evaluated on Seroprevalence of CSFV antibodies by indirect ELISA. The seroprevalence of classical swine fever virus in apparently healthy unvaccinated pigs in Mizoram was 34.68%, while molecular detection in symptomatic vaccinated pigs was 11.60%.
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