The reaction of α‐(aryl)‐4‐morpholineacetonitriles (masked aroyl anion equivalents) with N‐protected 4(5)‐bromo‐5(4)‐nitro‐1H‐imidazoles gave 4‐aroyl‐5‐nitroimidazoles which were reduced to afford 4‐aroyl‐5‐aminoimidazoles.
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Albright et al. (1986) studied this question.
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