Key result
Echocardiographic functional and 2D-STE-derived strain parameters in healthy Retrievers were largely independent of breed, age, and body weight, while LV dimensions were associated with body weight.
Why the study?
Breed, age, and body weight affect echocardiographic parameters, prompting evaluation of their effects in three breeds of clinically healthy Retrievers.
Do breed, age, and body weight affect standard and 2D speckle-tracking echocardiographic parameters in healthy Retrievers?
Observational (n=46)
Do breed, age, and body weight affect standard and 2D speckle-tracking echocardiographic parameters in healthy Retrievers?
In healthy Retrievers, most standard functional and 2D speckle-tracking echocardiographic parameters are independent of breed, age, and body weight, establishing a baseline for veterinary cardiac assessment.
Functional norms may apply across healthy Retrievers irrespective of size; leaves open validation in disease and other breeds.
Standard echocardiography is vital for the assessment of cardiac performance in healthy and diseased animals. Similarly, two-dimensional speckle-tracking echocardiography (2D-STE) is an advanced echocardiographic technique that is becoming increasingly important for the assessment of myocardial function. Breeds, age, and body weight (BW) are known to be important factors affecting the echocardiographic parameters; therefore, the aim of this study was to evaluate the effect of breed, age, and BW on the echocardiographic parameters in three breeds of clinically healthy Retrievers. A total of 46 Retrievers, including 16 Flat-coated Retrievers (FR), 16 Golden Retrievers (GR), and 14 Labrador Retrievers (LR) were included in the study. The comparison of the breeds revealed significant differences in the LV wall thickness of FR and GR, although further analysis using MLR showed that the differences were most likely associated with BW, similarly to the other LV dimensions. Functional parameters, including ejection fraction, fractional shortening, and left-atrial-to-aortic ratio, were independent of breed, age, and BW. On the other hand, peak aortic blood flow velocity, trans-mitral rapid ventricular filling flow, and the ratio of trans-mitral rapid ventricular filling flow to atrial contraction were influenced by age. The 2D-STE-derived radial and circumferential strain parameters were independent of breed, age, and BW, except for global strain in the radial direction.
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Hamabe et al. (2022) conducted an observational in Healthy Retrievers (n=46). Breed, age, and body weight was evaluated on Echocardiographic parameters (LV dimensions, functional parameters, and 2D-STE-derived strain). Echocardiographic functional and 2D-STE-derived strain parameters in healthy Retrievers were largely independent of breed, age, and body weight, while LV dimensions were associated with body weight.
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