Key result
F-18 FDG PET/CT imaging successfully documented the response to aggressive salvage chemotherapy in a patient with metastatic right atrial tumor thrombus from choriocarcinoma.
Case Report (n=1)
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F-18 FDG PET/CT is a useful noninvasive modality for diagnosing metastatic tumor thrombi in the right atrium and pulmonary vessels and for objectively assessing treatment response.
We report the case of an asymptomatic 38-year-old woman with persistent choriocarcinoma, based on the results of F-18 fluorodeoxyglucose positron emission tomography (F-18 FDG PET/CT) followed by CT pulmonary angiography, a diagnosis of metastatic right atrial tumor thrombus with pulmonary tumor thromboemboli was made. The patient underwent aggressive salvage chemotherapy with a combination of 5 drugs (ifosfamide, cisplatin, etoposide, vinblastine, and bleomycin) and responded to therapy which was objectively documented by the F-18 FDG PET/CT imaging. Thus FDG-PET/CT is a useful modality for demonstrating metastatic tumor thrombi noninvasively, mapping the extent of metastasis and assessing the response to therapy objectively.
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Tripathi et al. (2009) conducted a case report in Metastatic choriocarcinoma with tumor thrombus in the right atrium and pulmonary vessels (n=1). F-18 FDG PET/CT imaging and salvage chemotherapy was evaluated on Response to therapy and mapping of metastasis. F-18 FDG PET/CT imaging successfully documented the response to aggressive salvage chemotherapy in a patient with metastatic right atrial tumor thrombus from choriocarcinoma.
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