Key result
18F-FDG PET/CT successfully identified an unusually large tumor thrombus in the superior vena cava and demonstrated the pattern of metastatic disease in a patient with triple negative breast cancer.
Case Report (n=1)
18F-FDG PET/CT can effectively identify unusually large tumor thrombi in the superior vena cava and map disease recurrence in breast cancer patients.
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May aid detection of rare SVC tumor thrombi in TNBC; leaves open need for prospective validation before clinical adoption.
A 60-year-old female with triple negative breast cancer, postsurgery, neoadjuvant chemotherapy and radiotherapy, on follow-up had facial puffiness and giddiness. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) done for suspected recurrence evaluation revealed a large tumor thrombus (TT) in superior vena cava (SVC) with radiological evidence of SVC obstruction. 18F-FDG PET/CT also showed evidence of FDG avid brain metastases, lymph nodal metastases, and metastatic soft tissue deposits. This case of unusually large TT in SVC detected on 18F-FDG PET/CT highlights the ability of 18F-FDG PET/CT to identify TT and clearly demonstrate the pattern of disease in suspected recurrence in triple negative breast cancer patients.
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Sasikumar et al. (2017) conducted a case report in Triple negative breast cancer (n=1). 18F-FDG PET/CT was evaluated on Detection of tumor thrombus and disease recurrence. 18F-FDG PET/CT successfully identified an unusually large tumor thrombus in the superior vena cava and demonstrated the pattern of metastatic disease in a patient with triple negative breast cancer.
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