Key result
Joint erosions significantly declined across the decades from 1962 to 1992 in female patients with seropositive rheumatoid arthritis of 10-15 years' duration.
Why the study?
Has the long-term outcome (joint erosions) of rheumatoid arthritis improved over the decades from 1962 to 1992?
Population
50 female patients with seropositive rheumatoid arthritis of 10-15 years' duration from 1962, 1972, 1982 and…
Design
Cohort, evaluated blindly for erosions
Follow-up
10-15 years (disease duration)
Authors
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May indicate better long-term RA outcomes in seropositive women; leaves open drivers such as treatment evolution versus secular factors.
Observational (n=50)
Blinded
Has the long-term outcome (joint erosions) of rheumatoid arthritis improved over the decades from 1962 to 1992?
The severity of joint erosions in rheumatoid arthritis has significantly declined over the decades from 1962 to 1992, indicating improved long-term outcomes.
Heikkilä et al. (1994) conducted an observational in Seropositive rheumatoid arthritis (n=50). Decade of evaluation (1962, 1972, 1982, 1992) vs. Earlier decades was evaluated on Erosions in finger joints, wrists, and foot joints. Joint erosions significantly declined across the decades from 1962 to 1992 in female patients with seropositive rheumatoid arthritis of 10-15 years' duration.
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