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The International Working Group on the Diabetic Foot has now conducted two systematic reviews of the evidence of effectiveness of interventions to enhance the healing of chronic ulcers of the foot in diabetes. The first reviewed publications up to 2006 and the second from 2006–2010. Each review searched for published controlled trials or cohort studies in which the response to the intervention being tested was compared with a control group. The following guidelines are based on the evidence derived from them. None declared.
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Game et al. (2012) studied this question.
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