Key result
Platelet derived growth factor isoforms have different effects on DNA synthesis and migration in human vascular smooth muscle cells.
Population
Human vascular smooth muscle cells
Design
Preclinical
Authors
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Differential PDGF effects on VSMCs should not change practice; leaves open isoform-selective targeting in vascular disease.
Clunn et al. (1995) studied this question. Platelet Derived Growth Factor Isoforms was evaluated on DNA synthesis and migration. Platelet derived growth factor isoforms have different effects on DNA synthesis and migration in human vascular smooth muscle cells.
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