Key result
Administration of 2 g/day of vancomycin improved symptoms of toxic shock syndrome caused by TSST-1-producing MRSA in a 32-year-old woman with systemic lupus erythematosus after delivery.
Case Report (n=1)
Toxic shock syndrome should be considered as a potential complication in SLE patients presenting with severe systemic symptoms after delivery, as it can mimic SLE exacerbation.
We experienced a SLE patient with TSS after delivery. A 32-year-old SLE patient was transferred to our division due to fever, diarrhea, erosive rash, pericardial effusion, myalgia, low blood pressure, thrombocytopenia and hypoproteinemia which appeared two days after transvaginal delivery. At the time of admission, we considered these symptoms as the exacerbation of SLE, and treatment with high doses of steroid was started. It was when TSST-1-producing-MRSA was cultured from the vagina and uterus that TSS was suspected. 2 g/day of vancomycin was administered and her symptoms improved. As observed in this case, it is important to consider TSS as one of the complications seen with SLE patients after delivery.
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KADOYA et al. (1996) conducted a case report in Systemic Lupus Erythematosus and Toxic Shock Syndrome (n=1). Vancomycin was evaluated on Clinical improvement. Administration of 2 g/day of vancomycin improved symptoms of toxic shock syndrome caused by TSST-1-producing MRSA in a 32-year-old woman with systemic lupus erythematosus after delivery.
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