Key result
Prophylactic temporary transvenous cardiac pacemaker insertion during carotid angioplasty and stenting safely managed hemodynamic changes, triggering pacing in 22% of procedures.
Why the study?
Does prophylactic temporary transvenous cardiac pacemaker insertion safely prevent severe hemodynamic changes during carotid angioplasty and stenting in patients with carotid artery occlusive disease?
Observational (n=48)
No
Does prophylactic temporary transvenous cardiac pacemaker insertion safely prevent severe hemodynamic changes during carotid angioplasty and stenting in patients with carotid artery occlusive disease?
Prophylactic temporary transvenous pacing during carotid angioplasty and stenting is a safe and feasible strategy to manage periprocedural bradycardia and reduce the need for pharmacologic support.
Although many current series document the safety of carotid angioplasty and stenting procedures (CAS), several acknowledge clinically significant hemodynamic disturbances in 25-71% of patients. We report herein the safety and efficacy of prophylactic percutaneous temporary transvenous cardiac pacemaker insertion during CAS for the prevention of hemodynamic changes. At a community-based institution, 48 patients undergoing 51 attempted CAS procedures from March 1999 to August 2002 for carotid artery occlusive disease were retrospectively reviewed. Thirty-one percent of patients had procedures performed for either recurrent disease or a history of neck radiation; 62.5% had significant coronary disease. Temporary transvenous pacemakers were inserted as an adjunctive procedure in the authors' CAS protocol. The pacers were set to capture a heart rate decrease below 60 beats per minute. Demographics, cardiac risk, and outcomes were analyzed. CAS was successfully performed in 96% (49 lesions). In the intent-to-treat group, the patients had a mean age of 71 +/-9 years and angiographic stenoses of 88 +/-8%, with 29% having symptomatic lesions. Significant bradycardia or asystole to trigger ventricular pacing occurred in 11 (22%) procedures, thus, triggering ventricular pacing. Pharmacologic support for concomitant hypotension was temporarily necessary in only 4 (8%) cases. No patient required prolonged pacing or medication therapy following CAS. Neither presence of carotid-related symptoms nor disease etiology was related to need for intraprocedural pacing. Furthermore, there was no occurrence of pacemaker failure or other complication secondary to venous catheterization. Hemodynamic changes may occur during mechanical dilation of the carotid artery and bulb, with reports in the literature of the need for prolonged pharmacologic support. In selected patients, the prophylactic placement of a transvenous pacemaker is a safe, feasible, and expeditious method to treat periprocedural hemodynamic changes with a decrease in additional pharmacologic support during CAS.
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Bush et al. (2004) conducted an observational in Carotid artery occlusive disease (n=48). Prophylactic temporary transvenous cardiac pacemaker insertion was evaluated on Significant bradycardia or asystole triggering ventricular pacing. Prophylactic temporary transvenous cardiac pacemaker insertion during carotid angioplasty and stenting safely managed hemodynamic changes, triggering pacing in 22% of procedures.
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