Key result
In patients with inferior myocardial infarction, concurrent right ventricular involvement was associated with a higher rate of false-positive ECG assessment of thrombolysis efficiency (42.9% vs 15.9%, p<0.005).
Why the study?
The study was conducted to evaluate the outcomes of thrombolytic therapy and the accuracy of electrocardiographic assessment of thrombolysis efficiency in inferior myocardial infarction with and without right ventricular involvement.
Does right ventricular involvement affect the efficacy of thrombolytic therapy and the accuracy of electrocardiographic assessment of reperfusion in patients with inferior myocardial infarction?
Observational (n=118)
Does right ventricular involvement affect the efficacy of thrombolytic therapy and the accuracy of electrocardiographic assessment of reperfusion in patients with inferior myocardial infarction?
Absolute Event Rate: 42.9% vs 15.9%
p-value: p=<0.005
In patients with inferior myocardial infarction and right ventricular involvement, standard ST-segment resolution criteria (≥50% decrease) are inaccurate for assessing thrombolysis success, requiring ST-segment return to the isoline to avoid false-positive assessments.
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ECG assessment of thrombolysis may be unreliable in inferior MI with RV involvement; leaves open prospective validation of alternative criteria.
Мазур et al. (2021) conducted an observational in Inferior myocardial infarction (n=118). Right ventricular myocardial infarction (RVMI) vs. Without RVMI was evaluated on False-positive assessment of thrombolysis efficiency (p=<0.005). In patients with inferior myocardial infarction, concurrent right ventricular involvement was associated with a higher rate of false-positive ECG assessment of thrombolysis efficiency (42.9% vs 15.9%, p<0.005).
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