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The proposed investigation was carried out to evaluate the antihyperglycemic potential and to explore the structureactivity relationship (SAR) of a series of 28 hybrid sulfonylurea-linked chalconoids using streptozotocin-induced type 2 diabetic rats. Among all the compounds tested, compound SC 21 exhibited remarkable antidiabetic activity.
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Raju et al. (2018) studied this question.
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