Y‐Chromosome Deletions and Male Infertility: State of the Art and Clinical Implications

This finding led to the proposal that a gene, or a set of genes, that is required for spermatogenesis resides on the long (q) arm of the Y chromosome.This region of the Y chromosome was dubbed AZF since it appeared to harbor an a.zoospermia factor gene.More recently, the Y chromosome was mapped with high resolution into a series of seven deletion intervals