Key result
Pressure and volume overload induce distinct gene expression profiles in cardiac hypertrophy, with 93 genes modulated only by pressure overload and 134 selectively altered by volume overload.
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This editorial highlights the importance of transcriptomic profiling to understand the distinct molecular mechanisms driving concentric versus eccentric cardiac hypertrophy.
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Toko et al. (2006) conducted an editorial in Cardiac hypertrophy. Pressure and volume overload induce distinct gene expression profiles in cardiac hypertrophy, with 93 genes modulated only by pressure overload and 134 selectively altered by volume overload.
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