Cardiovascular risk scores in asymptomatic carotid stenosis: A validation study with ultrasonographic parameters

Fig 1. Comparison of ROC curves of novel risk prediction models for relevant ischemic stroke. A. Different models based on the FSRS for prediction of relevant ischemic stroke. ROC curves in the FSRS (black line), Model 1 (FSRS, PSV, CIMT, high-risk plaque, and PI, red line), Model 2 (FSRS, PSV ratio, CIMT, high-risk plaque, and PI, green line), and Model 3 (FSRS, PSV/EDV ratio, CIMT, high-risk plaque, and PI, blue line) are shown. B. Different models based on the ASCVD risk score for prediction of relevant ischemic stroke. ROC curves in ASCVD risk score (black line), Model 1 (ASCVD, PSV, CIMT, high-risk plaque, and PI, red line), Model 2 (ASCVD, PSV/EDV ratio, CIMT, high-risk plaque, and PI, green line), and Model 3 (ASCVD, PSV ratio, CIMT, high-risk plaque, and PI, blue line) are shown. Abbreviations: ROC, receiver operating characteristics; FSRS, Framingham stroke risk score; PSV, peak-systolic velocity; CIMT, common carotid artery intima-media thickness; PI, pulsatility index; PSV/EDV ratio, peak-systolic-and-end-diastolic-velocity-ratio; ASCVD, atherosclerotic cardiovascular disease. *indicates statistically significant (p<0.05) differences relative to classical cardiovascular risk…

Fig 2. Comparison of ROC curves of novel risk prediction models for composite outcomes. A. Different models based on the FSRS for prediction of composite outcomes. ROC curves in the FSRS (black line), Model 1 (FSRS, PSV ratio, CIMT, high-risk plaque, collateral flow, MFV, and PI, red line), Model 2 (FSRS, PSV/EDV ratio, CIMT, high-risk plaque, collateral flow, MFV, and PI, green line), and Model 3 (FSRS, PSV, CIMT, high-risk plaque, collateral flow, and PI, blue line) are shown. B. Different models based on the ASCVD risk score for prediction of composite outcomes. ROC curves in the ASCVD risk score (black line), Model 1 (ASCVD, PSV, CIMT, high-risk plaque, and PI, red line), Model 2 (ASCVD, PSV/EDV ratio, CIMT, MFV, and PI, green line), and Model 3 (ASCVD, PSV ratio, CIMT, MFV, and PI, blue line) are shown. *indicates statistically significant (p<0.05) differences relative to classical cardiovascular risk scores (black lines). Abbreviations: ROC, receiver operating characteristics; FSRS, Framingham stroke risk score; PSV, peak-systolic velocity; CIMT, common carotid artery intima-media thickness; MFV, mean flow velocity; PI, pulsatility index; PSV/EDV ratio,…

Fig 3. A graphical illustration of key findings. The improvement of predictive performance of the novel risk prediction models for asymptomatic carotid stenosis using combination with ultrasonographic parameters and conventional cardiovascular risk scores. Abbreviations: ACS, asymptomatic carotid stenosis.