Key result
Gated SPECT correlated well with two-dimensional echocardiography for assessing left ventricular ejection fraction (r=0.72, P<0.01), but yielded significantly higher end-diastolic and systolic volumes.
Why the study?
Does gated SPECT correlate with two-dimensional echocardiography for assessing left ventricular function and volumes in patients with dilated cardiomyopathy?
Population
45 patients with dilated cardiomyopathy (30 ischaemic, 15 non-ischaemic) and 10 normal control subjects.
Comparison
Gated myocardial perfusion SPECT vs Two-dimensional echocardiography
Design
Cross-sectional
Authors
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May support gated SPECT for LVEF in DCM; leaves open volume accuracy versus echocardiography.
Cross-Sectional (n=55)
Does gated SPECT correlate with two-dimensional echocardiography for assessing left ventricular function and volumes in patients with dilated cardiomyopathy?
Effect estimate: r=0.72
Absolute Event Rate: 27% vs 29%
p-value: p=<0.01
Gated SPECT is an effective alternative to 2D echocardiography for evaluating LV function and volumes in DCM, with the added benefit of assessing myocardial perfusion.
Berk et al. (2005) conducted a cross-sectional in Dilated cardiomyopathy (n=55). Gated myocardial perfusion SPECT vs. Two-dimensional echocardiography was evaluated on Left ventricular ejection fraction (LVEF) (r=0.72, p=<0.01). Gated SPECT correlated well with two-dimensional echocardiography for assessing left ventricular ejection fraction (r=0.72, P<0.01), but yielded significantly higher end-diastolic and systolic volumes.