Mixed tumors and carcinosarcomas of the uterus evaluated five years after treatment

A clinicopathologic study of 66 patients with 33 heterologous tumors and 33 carcinosarcomas followed for 5 years after treatment is presented. The significantly better prognosis of the carcinosarcoma patients supports the opinion that subclassification of these types of neoplasms has practical value. The survival rate for both groups of tumors is influenced by the degree of myometrial invasion and the patient's age; these 2 factors bear an inverse relationship to survival time. A second malignant tumor was diagnosed in 7.5% of the patients. Prior irradiation was not an important factor. In this material, the 5-year overall survival rate was 30% for mixed mesodermal (heterologous) tumors and 43.7% for the carcinosarcomas.