Electrochemical Silylation of Electron‐Deficient Heterocycles Using N ‐Hydroxyphthalimide as HAT Catalyst

A practical electrochemical Minisci‐type reaction for the synthesis of silylated heterocycles is described. Using N ‐hydroxyphthalimide (NHPI) as the hydrogen atom transfer (HAT) catalyst and trialkylsilanes as the silyl radical sources, a wide range of electron‐deficient heterocycles in‐cluding quinoline, quinoxaline, phthalazine, 3,6‐dichloropyridazine, phenanthridine, 6‐chloroimidazo[1,2‐ b ]pyridazine and coumarin, etc. were easily converted to the corresponding silylated products in 37–83% yields. magnified image