A novel type of amphiphilic spherosilsesquioxane derivative, 1-(1,ω-propylenemethoxy)oligo(ethylene oxide)-3,5,7,9,11,13,15-heptahydridopentacyclo[9.5.1 3,9 .1 5,15 .1 7,13 ]octasiloxane has been prepared from (HSiO 3/2 ) 8 and allyl-functional oligo(ethyleneoxide) ( M n = 750 g/mol) by hydrosilylation. The monosubstituted octahydridosilsesquioxane was characterized by 1 H, 13 C, and 29 Si NMR spectroscopy, IR, and MALDI-TOF mass spectroscopy as well as elemental analysis. Surface tension measurements of the water-soluble amphiphile show a cmc in the range of 6 × 10 - 4 mol/L. Aggregation of the uncondensed amphiphile leads to micellar and vesicular structures that can be cross-linked to liposome-like silica particles at elevated pH.
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Knischka et al. (1999) studied this question.
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