Fever Associated with Juvenile Rheumatoid Arthritis

THE relation of fever to juvenile rheumatoid arthritis appears to have been largely overlooked in the period of almost seventy years since Still1 first called attention to certain distinctive pyrexial patterns. Furthermore, the disease is hardly ever considered in the differential diagnosis of so-called fevers of unknown origin. Yet fever alone, or together with rash2 and other nonarticular features, frequently precedes arthritic manifestations of juvenile rheumatoid arthritis.Fever has been noted in 42 to 90 per cent of close to 1000 cases reported in the literature since 1958.3 4 5 6 7 8 9 10 11 12 13 So little attention has been paid to this association, however, that only . . .