Specific Recognition of Disaccharides in Water by an Artificial Bicyclic Carbohydrate Receptor

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We present the synthesis of a peptide‐based bicyclic carbohydrate receptor capable of carbohydrate recognition in 10 % deuterated acetic acid in water. The binding constants were estimated by using NMR spectroscopy, and furthermore, a series of carbohydrate complexes were studied with the use of MS (ESI) of the complex. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)