Key result
Coronary flow reserve was significantly lower in the left circumflex artery than the LAD or RCA (P<0.01), and lower in younger versus older children with angiographically normal coronary arteries.
Population
30 children with Kawasaki's disease without angiographic coronary lesions.
Design
Cross-sectional
Authors
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May inform vessel- and age-specific pediatric CFR norms; hypothesis-generating without outcome linkage.
Observational (n=30)
p-value: p=<0.01
Coronary flow velocity dynamics in children with normal coronary arteries show vessel-specific and age-dependent physiological characteristics, with lower coronary flow reserve in younger children.
Hamaoka et al. (1995) conducted an observational in Kawasaki's disease with angiographically normal coronary arteries (n=30). Age (younger vs older) and coronary vessel type vs. Older age group and LAD/RCA vessels was evaluated on Coronary flow reserve (CFR) (p=<0.01). Coronary flow reserve was significantly lower in the left circumflex artery than the LAD or RCA (P<0.01), and lower in younger versus older children with angiographically normal coronary arteries.
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