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Abstract 5‐Fluoroisatin was condensed with various o‐phenylenediamines to yield substituted 9‐fluoroindophenazines 1. A similar reaction of 1‐methyl‐5‐fluoroisatin with o‐phenylenediamines furnished 6‐methyl‐9‐fluoroindophenazines 2. The Mannich reaction of 1 with secondary amines gave rise to substituted 6‐aminomethyl‐9‐fluorindophenazines 3. Compounds 1–3 have been tested for their insecticidal and antibacterial activity.
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Varma et al. (1981) studied this question.
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