Formation of Vesicular Structures through the Self‐Assembly of a Flexible Bis‐Zwitterion in Dimethyl Sulfoxide

Small molecule, large structures: The connection of two zwitterionic binding motifs with a lipophilic alkyl linker results in an amphiphilic bis-zwitterion, which forms self-assembled vesicles even in polar solutions. The data suggest that two bis-zwitterions dimerize and then further aggregate to form vesicles, most likely driven by H-bonding and van der Waals interactions between the linkers.