Asymmetric Reduction of Imines.

This is the authors' abstract. We don't add key points for this paper.

Of all options enantioselective reduction of imines is the most straightforward method for preparation of optically active amines. This asymmetric transformation can be accomplished by stoichiometric or catalytic hydroboration, aluminium hydride reduction, and, more efficiently, transition metal catalyzed reduction with organosilanes, molecular hydrogen, and formic acid. Various chiral catalysts containing Ti, Rh, Ir, and Ru have been developed for this purpose. This review summarizes the recent progress in this subject.