Key result
The frequency of metabolic syndrome among nondiabetic CAPD patients was 37.9% overall and decreased with longer dialysis duration.
Why the study?
Is the duration of continuous ambulatory peritoneal dialysis associated with the frequency of metabolic syndrome in nondiabetic patients?
Cross-Sectional (n=58)
Is the duration of continuous ambulatory peritoneal dialysis associated with the frequency of metabolic syndrome in nondiabetic patients?
In nondiabetic CAPD patients, the frequency of metabolic syndrome was 37.9% and appeared to decrease with longer dialysis duration.
Answers are grounded in this paper and cite their sources.
Metabolic syndrome frequency may decline with longer CAPD; hypothesis-generating association that requires prospective confirmation before practice change.
OBJECTivE: To evaluate the characteristics of patients with metabolic syndrome, and the association of developing MS with peritoneal dialysis duration among patients undergoing continuous ambulatory peritoneal dialysis. maTERial and mETHOdS: Fifty-eight nondiabetic CAPD patients were evaluated. Biochemical parameters, blood pressure, length, weight, waist circumference, and body mass indexes were recorded. MS was determined using NCP-ATP III criteria. The patients were divided into 3 groups according to dialysis duration (Group 1: ≤60 months, Group 2: 61-120 months, Group 3: ≥121 months) and the frequency of MS was compared. RESulTS: Twenty-four of 58 patients were male, and MS was present in 22 (37.9%) patients. 14 (82.4%) of 22 patients with MS were female, (p=0.544). There was a statistically significant difference between patients with and without MS regarding age, BMI, waist circumference, PD duration, and triglyceride levels (p<0.05). 55% (n=32) of the patients were in group 1, 34.5% (n=20) in group 2, and 10.5% (n=6) in group 3 (p=0.092). The frequency of MS decreased with prolongation of dialysis duration (50% in group 1, 20% in group 2, and 33,3% in group 3) (p<0.001). COnCluSiOn: The frequency of MS among our CAPD patients was 37.9% and it decreased with prolongation of dialysis duration. This result may suggest that alterations in metabolic state, and abandoning glucose-based PD solutions may improve MS criteria. KEY wORdS: Metabolic syndrome, Peritoneal dialysis, Metabolism, Cardiovascular risk Yazisma Adresi: Hasan KaYaBasi Dicle Universitesi Tip Fakultesi, Nefroloji Bilim Dali, Diyarbakir, Turkiye Gsm : 0 507 740 38 89 E-posta : drkayabasi@yahoo.com Gelis Tarihi : 31.12.2010 Kabul Tarihi : 19.02.2011 doi: 10.5262/tndt.2011.1002.09
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Kayabaşı et al. (2011) conducted a cross-sectional in Continuous ambulatory peritoneal dialysis (CAPD) (n=58). Prolonged peritoneal dialysis duration vs. Shorter dialysis duration (≤60 months) was evaluated on Frequency of metabolic syndrome (p=<0.001). The frequency of metabolic syndrome among nondiabetic CAPD patients was 37.9% overall and decreased with longer dialysis duration.
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