Key result
Patients with acute myopericarditis and residual abnormalities presented altered lymphocyte subsets, including increased B1 and reduced OKT8 cells with an elevated OKT4/8 ratio.
Observational (n=81)
An imbalance of helper/suppressor T cells may modulate the clinical course of acute myopericarditis, potentially contributing to residual myocardial damage or chronic inflammation.
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May associate lymphocyte imbalance with residual myopericarditis damage; hypothesis-generating and requires prospective validation before any clinical use.
Koga et al. (1989) conducted an observational in Acute myopericarditis, arrhythmias, and dilated cardiomyopathy (n=81). Altered lymphocyte subsets vs. Patients who recovered completely without residual abnormalities was evaluated on Frequencies of lymphocyte subsets. Patients with acute myopericarditis and residual abnormalities presented altered lymphocyte subsets, including increased B1 and reduced OKT8 cells with an elevated OKT4/8 ratio.