Key result
The renin-angiotensin system plays a fundamental role in kidney development, hemo-vasculogenesis, hematopoiesis, and the development of hypertension due to reduced nephron number.
Design
Review
Authors
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Informs developmental hypertension mechanisms; extends preclinical insights but leaves open clinical translation.
This review summarizes the fundamental role of the renin-angiotensin system in kidney development and its implications for hypertension and renal fibrosis.
Sequeira-Lόpez et al. (2003) conducted a review in Kidney embryogenesis and kidney abnormalities. Angiotensin II was evaluated. The renin-angiotensin system plays a fundamental role in kidney development, hemo-vasculogenesis, hematopoiesis, and the development of hypertension due to reduced nephron number.
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