Key result
Biatrial ablation was more effective than isolated left atrial ablation in maintaining sinus rhythm at 24 months (58% vs 31%, p=0.019) in patients with long-standing persistent AF undergoing CABG.
Why the study?
The comparative results of biatrial versus left atrial ablation in patients with long-standing persistent AF and CAD undergoing CABG needed evaluation.
Does biatrial ablation improve maintenance of sinus rhythm compared to left atrial ablation in patients with long-standing persistent AF undergoing CABG?
RCT (n=116)
blinded
randomized
No
Does biatrial ablation improve maintenance of sinus rhythm compared to left atrial ablation in patients with long-standing persistent AF undergoing CABG?
Absolute Event Rate: 58% vs 31%
p-value: p=0.019
Biatrial ablation is significantly more effective than isolated left atrial ablation for maintaining sinus rhythm at 24 months in patients with long-standing persistent AF undergoing CABG.
Biatrial ablation outperforms left atrial ablation for 24-month sinus rhythm maintenance during CABG in long-standing persistent AF; extends RCT evidence favoring comprehensive lesion sets.
Purpose. To compare the results of biatrial (BA) and left atrial ablation (LAA) performed in patients with long-standing persistent atrial fibrillation (AF) with concomitant coronary artery disease (CAD) with indication for coronary artery bypass grafting (CABG). Material and Methods. A prospective, randomized, single-center, blinded study was conducted on the basis Meshalkin National Medical Research Center in the period from 2016 to 2019. A total of 116 patients with long-standing persistent AF and CAD were randomized into two groups: BA + CABG group (n = 58) and LAA + CABG group (n = 58). Patients of both groups underwent CABG surgery with the chosen atrial ablation technique (LAA or BA). Results: BA technique proved to be more effective in maintaining sinus rhythm (58%) compared with isolated LAA (31%) at 24 months (p = 0.019) after surgical treatment of long-standing persistent AF with concomitant CABG. Conclusion: BA technique was more effective than isolated LAA in the late postoperative period of 24 months.
No takes yet. Share an insight, caveat, or question.
Kalybekova et al. (2021) conducted an RCT in long-standing persistent atrial fibrillation and coronary artery disease (n=116). Biatrial ablation vs. Left atrial ablation was evaluated on maintaining sinus rhythm (p=0.019). Biatrial ablation was more effective than isolated left atrial ablation in maintaining sinus rhythm at 24 months (58% vs 31%, p=0.019) in patients with long-standing persistent AF undergoing CABG.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: