Key result
Mitral valve surgery in patients with mitral regurgitation and LVEF <30% resulted in a 5-year survival rate of 77% and improved mean ejection fraction from 23.1% to 36% (p<0.02).
Why the study?
Does isolated mitral valve surgery improve outcomes in patients with mitral regurgitation and severe left ventricular dysfunction (LVEF <30%)?
Population
31 patients with mitral regurgitation and a left ventricular ejection fraction of below 30% on maximal drug…
Design
Cohort
Follow-up
mean 39 +/- 16 months
Authors
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May support surgery in selected patients with severe LV dysfunction and MR; leaves open randomized confirmation of benefit.
Cohort (n=31)
Does isolated mitral valve surgery improve outcomes in patients with mitral regurgitation and severe left ventricular dysfunction (LVEF <30%)?
Mitral valve surgery in selected patients with severe left ventricular dysfunction and mitral regurgitation is associated with acceptable survival and significant improvements in symptoms and ejection fraction.
Rothenburger et al. (2002) conducted a cohort in Mitral regurgitation and severe left ventricular dysfunction (n=31). Mitral valve surgery was evaluated on 5-year survival rate. Mitral valve surgery in patients with mitral regurgitation and LVEF <30% resulted in a 5-year survival rate of 77% and improved mean ejection fraction from 23.1% to 36% (p<0.02).
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