Key result
Long-term warfarin treatment for atrial fibrillation in older adults did not significantly affect mental or physical quality of life compared with the general population aged over 75 years.
Why the study?
Does long-term warfarin treatment affect the quality of life in elderly patients with atrial fibrillation?
Population
330 elderly patients taking warfarin for thromboprophylaxis of atrial fibrillation, living in the community…
Comparison
Established warfarin therapy (duration >1 year) vs Recent warfarin therapy and the general…
Design
Cross-sectional
Authors
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Warfarin was not associated with worse QoL in elderly AF patients; leaves open net benefit versus alternatives and needs prospective confirmation.
Cross-Sectional (n=330)
Does long-term warfarin treatment affect the quality of life in elderly patients with atrial fibrillation?
Long-term warfarin treatment does not negatively impact the physical or mental quality of life of elderly patients with atrial fibrillation compared to the general population, supporting its judicious use in this demographic.
Das et al. (2006) conducted a cross-sectional in Atrial fibrillation (n=330). Warfarin therapy vs. General population aged >75 years was evaluated on Quality of life (Mental and Physical Component Scores on SF12v2). Long-term warfarin treatment for atrial fibrillation in older adults did not significantly affect mental or physical quality of life compared with the general population aged over 75 years.
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