Key result
Esophageal vago-afferent electrostimulation at intensities ≥5 mA shifted the heart rate power spectrum towards enhanced vagal modulation, with no significant effect on overall heart rate.
Why the study?
Does esophageal vago-afferent electrostimulation alter cardiac vagal modulation in healthy male subjects?
Population
10 healthy male subjects, mean age 23.9 +/- 6.3 years
Comparison
Esophageal vago-afferent electrostimulation… vs Baseline measurements
Design
Other, Stimulus intensities applied in random order
Authors
Loading...
May support vagal modulation research in healthy subjects; leaves open clinical translation or therapeutic applications.
Does esophageal vago-afferent electrostimulation alter cardiac vagal modulation in healthy male subjects?
Electrical stimulation of the distal esophagus elicits a reproducible shift in the heart rate power spectrum towards enhanced vagal modulation in healthy subjects.
Markad Kamath (1998) studied healthy (n=10). Esophageal vago-afferent electrostimulation vs. baseline was evaluated on heart rate power spectra and cerebral evoked potentials. Esophageal vago-afferent electrostimulation at intensities ≥5 mA shifted the heart rate power spectrum towards enhanced vagal modulation, with no significant effect on overall heart rate.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: