ACTH and Adrenocorticosteroids as Therapeutic Adjuncts in Infectious Diseases

TuberculosisIn contrast to most of the infectious diseases discussed above, tuberculosis is a more chronic disease, characterized by a granulomatous and caseating type of inflammation involving many different organs and tissues. The inflammatory reaction of the tissues in tuberculosis is also related, in part, to the acquired hypersensitivity of the host to components of the tubercle bacilli. In view of the chronicity and debilitating nature of tuberculosis, with its slow response to chemotherapy, it appeared quite logical to explore the influence of ACTH and the adrenal steroids on the course of the disease, both in experimentally infected animals and . . .