What question did this study set out to answer?

To determine the impact of the 2018 UNOS six-tier heart allocation system change on competing waitlist outcomes across various listing strategies.

May 12, 2021Clinical Transplantation

Impact of heart transplant allocation change on competing waitlist outcomes among listing strategies

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Authors

JPJay PatelJohns Hopkins University JCJoshua ChungUniversity of California, San Francisco ASAhmed SeliemNewark Beth Israel Medical Center

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Implication

Cohort study reveals reduced waitlist mortality and increased transplantation across listing strategies in adult heart transplant candidates, indicating broader efficacy of the revised allocation...

Key Points

To determine the impact of the 2018 UNOS six-tier heart allocation system change on competing waitlist outcomes across various listing strategies.
Included all adult patients (N = 17,422) listed for first-time heart transplantation in the UNOS registry between October 17, 2015, and June 12, 2020.
Categorized candidates by support strategy at listing: no support, inotropes, intra-aortic balloon pump, durable LVAD, temporary VAD, and ECMO.
Used Fine-Gray proportional subhazard models to estimate the effect of allocation policy change on competing waitlist outcomes of transplantation, death, or waitlist removal.
Waitlist mortality risk was significantly reduced after the allocation change across every listing strategy (p < .001) except for temporary VAD.
Transplantation rates increased significantly under the new allocation system across every listing strategy (p < .001) except for durable LVAD.

Cite This Study

Patel et al. (2021) studied this question.

synapsesocial.com/papers/6a9ea4fb33946b5f8d2cc391 https://doi.org/10.1111/ctr.14345

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Implication

Cohort study reveals reduced waitlist mortality and increased transplantation across listing strategies in adult heart transplant candidates, indicating broader efficacy of the revised allocation...

Impact of heart transplant allocation change on competing waitlist outcomes among listing strategies

Discussion

Member takes

Implication

Key Points

Cite This Study

Impact of heart transplant allocation change on competing waitlist outcomes among listing strategies

Discussion

Member takes

Implication

Key Points

Cite This Study

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