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AIM: To critically evaluate previous scientific evidence on Fusobacterium's role in colorectal neoplasia development. METHODS: and its relationship with colorectal cancer (CRC) were included in the analysis. Abstracts, review articles, studies investigating other colonic diseases, and studies written in other languages than English were excluded from our analysis. Ninety articles were included after removing duplicates, resolving disagreements between the two reviewers, and applying the above criteria. RESULTS: strains carrying invasive properties and virulence factors such as FadA and FAP. Future prospective and experimental human studies would fill an important gap in this literature.
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Hussan et al. (2017) studied this question.
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