What question did this study set out to answer?

To evaluate midterm outcomes, mechanical circulatory support transitions, complications, and mortality risk factors in patients managed with extended Impella 5.5 support.

April 10, 2023ASAIO Journal

Extended Support With the Impella 5.5: Transplant, ECMO, and Complications

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To evaluate midterm outcomes, mechanical circulatory support transitions, complications, and mortality risk factors in patients managed with extended Impella 5.5 support.
Conducted a retrospective review of N=40 consecutive patients implanted with the Impella 5.5 at a single medical center across various bridging strategies.
Categorized support duration into <14 days (40%), 14–30 days (32.5%), and >30 days (27.5%), monitoring bridge-to-transplant, durable LVAD placement, ECMO conversion, and recovery.
Thirty-day mortality was 22.5% (9/40), with 62.5% (25/40) successfully bridged to heart transplant or durable LVAD, and 10.0% (4/40) achieving native heart recovery.
Among 9 patients with greater than moderate right ventricular dysfunction, 55.6% (5/9) achieved successful bridging, while all 5 patients (100%) requiring interval cannulation to VA-ECMO were successfully transplanted.
Lower pulmonary artery systolic pressure was significantly associated with increased mortality (P = 0.029).

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Implication

Retrospective study demonstrates effective bridge-to-transplant outcomes with extended Impella 5.5 support in cardiogenic shock, indicating feasibility for prolonged mechanical stabilization.

Cite This Study

Cohen et al. (2023) studied this question.

synapsesocial.com/papers/6a9eabc23a41fb039a11f1ff https://doi.org/10.1097/mat.0000000000001931

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Implication

Retrospective study demonstrates effective bridge-to-transplant outcomes with extended Impella 5.5 support in cardiogenic shock, indicating feasibility for prolonged mechanical stabilization.

Extended Support With the Impella 5.5: Transplant, ECMO, and Complications

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Discussion

Implication

Cite This Study

Extended Support With the Impella 5.5: Transplant, ECMO, and Complications

Key Points

Discussion

Implication

Cite This Study

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