Key result
Prolonged running followed by 45 minutes of low-intensity activity or rest increased maximal SR Ca2+-ATPase activity and Ca2+ uptake in rat skeletal muscle compared to controls (P < 0.05).
Population
Fast rat gastrocnemius muscles
Comparison
Prolonged running, prolonged running plus 45 min… vs Controls (Con)
Design
Preclinical
Authors
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Does not support changes in exercise protocols; leaves open mechanisms and human relevance of enhanced SR Ca2+ handling.
p-value: p=< 0.05
The increase in maximal SR Ca2+-ATPase activity after exercise recovery is not due to changes in enzyme nitrosylation, phosphorylation, binding affinity, or protein content.
Schertzer et al. (2003) studied this question. Prolonged running followed by low-intensity activity or rest vs. Controls was evaluated on Maximal SR Ca(2+)-ATPase activity (Vmax) and Ca(2+) uptake (p=< 0.05). Prolonged running followed by 45 minutes of low-intensity activity or rest increased maximal SR Ca2+-ATPase activity and Ca2+ uptake in rat skeletal muscle compared to controls (P < 0.05).
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